Scilex Pharmaceuticals - PharmaKB

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Company ReportsScilex Pharmaceuticals

Scilex Pharmaceuticals

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Gloperba	Colchicine	2019-01-30	2028-2037	Gonorrhea , Biliary liver cirrhosis , Amyloidosis , Neurosyphilis , Familial mediterranean fever , Gout
Ztlido	Lidocaine	2018-02-28	2026-2035	Pain , Ventricular tachycardia , Cardiac arrhythmias , Burns , Esophageal diseases , Ventricular fibrillation , Physiological sexual dysfunction , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia , Premature ejaculation , Sepsis , Urinary tract infections , Otitis media , Bacterial infections , Gonorrhea , Pseudomonas infections , Bacterial skin diseases , Escherichia coli infections , Pelvic infection , Soft tissue infections , Clostridium infections , Streptococcal infections , Lyme disease , Bacterial pneumonia , Staphylococcal infections , Proctocolitis , Peritonitis , Bacterial meningitis , Salmonella infections , Proteus infections , Infectious bone diseases , Acinetobacter infections , Klebsiella infections , Enteritis , Epididymitis , Chancroid , Bacteroidaceae infections , Serratia infections , Septic shock , Hypotension , Anaphylaxis , Bradycardia , Heart arrest , Open-angle glaucoma , Heart block , Airway obstruction , Bronchial spasm , Myocardial infarction , Migraine disorders , Pulmonary embolism , Postoperative complications , Thromboembolism , Cerebral infarction , Coronary thrombosis , Unstable angina , Orthostatic hypotension , Cluster headache , Postpartum hemorrhage , Xerostomia , Thrombophlebitis , Leukemia , Ulcerative colitis , Ankylosing spondylitis , Vomiting , Nausea , Sarcoidosis , Thrombocytopenic purpura idiopathic , Pulmonary tuberculosis , Mycosis fungoides , Systemic lupus erythematosus , Rheumatic diseases , Bursitis , Keratitis , Allergic rhinitis perennial , Thyroiditis , Iritis , Hypercalcemia , Brain edema , Pemphigus , Addison disease , Collagen diseases , Dermatitis herpetiformis , Acne vulgaris , Chlamydia infections , Syphilis , Borrelia infections , Gram-positive bacterial infections , Rickettsia infections , Mycoplasma infections , Protozoan infections , Psittacosis , Wounds and injuries , Gastrointestinal diseases , Pneumonia , Skin diseases , Bacterial eye infections , Urinary bladder diseases , Hepatic encephalopathy , Bacteremia , Empyema , Otitis externa , Haemophilus infections , Pseudomembranous enterocolitis , Postoperative pain
Elyxyb	Celecoxib	2020-05-05	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

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,

,

,

nociceptive pain

healthy volunteers/patients

,

tissue adhesions

,

alzheimer disease

,

cognitive dysfunction

,

prostatic hyperplasia

,

,

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

,

,

autism spectrum disorder

,

urinary bladder neoplasms

,

non-muscle invasive bladder neoplasms

,

autistic disorder

,

asperger syndrome

,

pervasive child development disorders

,

systemic lupus erythematosus

,

,

,

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

acinetobacter infections

,

communicable diseases

,

acquired immunodeficiency syndrome

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

,

,

psychological adaptation

,

,

,

immunologic deficiency syndromes

,

craniocerebral trauma

,

substance-related disorders

,

,

psychological stress

,

,

psychological distress

,

emotional regulation

,

,

,

post-traumatic stress disorders

,

suicidal ideation

,

attempted suicide

,

,

,

anxiety disorders

,

acupuncture therapy

,

drug interactions

,

parkinson disease

,

learning disabilities

,

pain management

,

,

Bos taurus adrenal cortex corticosteroids

,

colorectal neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

type 2 diabetes mellitus

,

diabetes mellitus

,

atopic dermatitis

,

,

,

,

,

ventilator-associated pneumonia

,

,

,

,

alcohol drinking

,

vascular stiffness

,

,

,

tissue adhesions

,

,

,

,

healthy volunteers/patients

,

peripheral nervous system diseases

,

chronic obstructive pulmonary disease

,

,

irritable bowel syndrome

,

,

diabetic neuropathies

,

breast neoplasms

,

,

colonic diseases

,

inflammatory bowel diseases

,

intestinal diseases

,

nervous system diseases

,

deglutition disorders

,

spinocerebellar degenerations

,

spinocerebellar ataxias

,

machado-joseph disease

,

,

,

ischemic stroke

,

,

,

cerebral infarction

,

corneal diseases

,

neurologic manifestations

,

parkinson disease

,

,

tobacco use disorder

,

tobacco smoking

,

smoking cessation

,

,

,

,

,

musculoskeletal pain

,

colonic neoplasms

,

stomach neoplasms

,

wounds and injuries

,

,

gastrointestinal endoscopy

,

pharyngeal diseases

,

,

esophageal neoplasms

,

,

,

prehypertension

,

aphthous stomatitis

,

,

,

,

diabetes mellitus

,

,

opioid-related disorders

,

,

knee osteoarthritis

,

,

,

dry eye syndromes

,

,

cesarean section

,

,

,

,

keratoconjunctivitis sicca

,

actinic keratosis

,

,

,

,

,

,

,

immunologic cytotoxicity

,

,

,

cigarette smoking

,

,

,

tobacco use cessation

,

,

,

olfaction disorders

,

migraine disorders

,

,

,

,

,

substance-related disorders

,

,

,

,

,

,

,

,

,

uterine cervical dysplasia

,

carpal tunnel syndrome

,

positron-emission tomography

,

obstructive sleep apnea

,

sleep apnea syndromes

,

perioperative nursing

,

nasal obstruction

,

,

,

environmental biomarkers

,

health behavior

,

oropharyngeal neoplasms

,

percutaneous coronary intervention

,

myocardial infarction

,

coronary artery bypass

,

,

type 2 diabetes mellitus

,

addictive behavior

,

,

tendon injuries

,

,

,

,

atopic dermatitis

,

,

,

,

,

neurogenic inflammation

,

musculoskeletal diseases

,

respiratory tract diseases

,

,

,

smoking reduction

,

postoperative nausea and vomiting

,

hospitalization

,

,

myofascial pain syndromes

,

,

postoperative pain

,

,

,

gallbladder diseases

,

,

neurocognitive disorders

,

,

opiate substitution treatment

,

minimally invasive surgical procedures

,

,

cognitive dysfunction

,

,

,

,

,

,

,

marijuana abuse

,

,

Antineoplaston a10

healthy volunteers/patients

,

intervertebral disc displacement

Histone-arginine methyltransferase carm1

pharmacokinetics

,

chronic obstructive pulmonary disease

,

respiratory aspiration

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

neuroinflammatory diseases

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

coronary disease

,

myocardial ischemia

,

interstitial lung diseases

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

hyperphosphatemia

,

multiple sclerosis

,

non-hodgkin lymphoma

,

,

chronic renal insufficiency

,

prostatic neoplasms

,

surgical blood loss

,

venous thrombosis

,

,

essential hypertension

,

kidney diseases

,

,

,

,

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

cardiovascular diseases

,

,

spinal cord injuries

,

peripheral arterial disease

,

renal artery obstruction

,

,

bacterial infections

,

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

cardiovascular abnormalities

,

pathologic constriction

,

,

vascular diseases

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

,

,

atopic dermatitis

,

liver neoplasms

,

,

,

communicable diseases

,

relapsing-remitting multiple sclerosis

,

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

acute coronary syndrome

,

tension-type headache

,

,

,

peripheral nervous system diseases

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

respiratory tract infections

,

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

community-acquired pneumonia

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

healthy volunteers/patients

,

coronary artery disease

,

esophageal neoplasms

,

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

chronic urticaria

,

,

type 1 diabetes mellitus

,

triple negative breast neoplasms

,

ovarian epithelial carcinoma

,

gastrointestinal endoscopy

,

renal cell carcinoma

,

cholangiocarcinoma

,

,

endometrial neoplasms

,

,

,

,

acute kidney injury

,

non-small-cell lung carcinoma

,

breast neoplasms

,

,

prostatic neoplasms

,

ovarian neoplasms

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

stomach neoplasms

,

urinary bladder neoplasms

,

,

human influenza

,

,

esophageal squamous cell carcinoma

,

hepatocellular carcinoma

,

liver neoplasms

,

hypertriglyceridemia

,

gastroesophageal reflux

,

,

respiratory distress syndrome

,

respiratory tract infections

,

,

coronavirus infections

,

respiratory insufficiency

,

severe acute respiratory syndrome

,

,

exercise-induced asthma

,

bronchial spasm

,

exercise-induced allergies

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

renal insufficiency

,

kidney function tests

,

,

thromboembolism

,

atherosclerosis

,

systemic lupus erythematosus

,

post-traumatic stress disorders

,

combat disorders

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