Scilex Pharmaceuticals - PharmaKB

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Company ReportsScilex Pharmaceuticals

Scilex Pharmaceuticals

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Gloperba	Colchicine	2019-01-30	2028-2037	Gonorrhea , Biliary liver cirrhosis , Amyloidosis , Neurosyphilis , Familial mediterranean fever , Gout
Ztlido	Lidocaine	2018-02-28	2026-2035	Pain , Ventricular tachycardia , Cardiac arrhythmias , Burns , Esophageal diseases , Ventricular fibrillation , Physiological sexual dysfunction , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia , Premature ejaculation , Sepsis , Urinary tract infections , Otitis media , Bacterial infections , Gonorrhea , Pseudomonas infections , Bacterial skin diseases , Escherichia coli infections , Pelvic infection , Soft tissue infections , Clostridium infections , Streptococcal infections , Lyme disease , Bacterial pneumonia , Staphylococcal infections , Proctocolitis , Peritonitis , Bacterial meningitis , Salmonella infections , Proteus infections , Infectious bone diseases , Acinetobacter infections , Klebsiella infections , Enteritis , Epididymitis , Chancroid , Bacteroidaceae infections , Serratia infections , Septic shock , Hypotension , Anaphylaxis , Bradycardia , Heart arrest , Open-angle glaucoma , Heart block , Airway obstruction , Bronchial spasm , Myocardial infarction , Migraine disorders , Pulmonary embolism , Postoperative complications , Thromboembolism , Cerebral infarction , Coronary thrombosis , Unstable angina , Orthostatic hypotension , Cluster headache , Postpartum hemorrhage , Xerostomia , Thrombophlebitis , Leukemia , Ulcerative colitis , Ankylosing spondylitis , Vomiting , Nausea , Sarcoidosis , Thrombocytopenic purpura idiopathic , Pulmonary tuberculosis , Mycosis fungoides , Systemic lupus erythematosus , Rheumatic diseases , Bursitis , Keratitis , Allergic rhinitis perennial , Thyroiditis , Iritis , Hypercalcemia , Brain edema , Pemphigus , Addison disease , Collagen diseases , Dermatitis herpetiformis , Acne vulgaris , Chlamydia infections , Syphilis , Borrelia infections , Gram-positive bacterial infections , Rickettsia infections , Mycoplasma infections , Protozoan infections , Psittacosis , Wounds and injuries , Gastrointestinal diseases , Pneumonia , Skin diseases , Bacterial eye infections , Urinary bladder diseases , Hepatic encephalopathy , Bacteremia , Empyema , Otitis externa , Haemophilus infections , Pseudomembranous enterocolitis , Postoperative pain
Elyxyb	Celecoxib	2020-05-05	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

knee osteoarthritis

healthy volunteers/patients

,

tissue adhesions

,

alzheimer disease

,

cognitive dysfunction

,

prostatic hyperplasia

,

,

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

,

,

autism spectrum disorder

,

urinary bladder neoplasms

,

non-muscle invasive bladder neoplasms

,

breast neoplasms

,

,

triple negative breast neoplasms

,

hemangiosarcoma

,

pathologic complete response

,

autistic disorder

,

asperger syndrome

,

pervasive child development disorders

,

systemic lupus erythematosus

,

,

,

acinetobacter infections

,

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

communicable diseases

,

bacterial pneumonia

,

acquired immunodeficiency syndrome

,

chronic obstructive pulmonary disease

,

,

,

,

obstructive lung diseases

,

psychological adaptation

,

anxiety disorders

,

,

,

immunologic deficiency syndromes

,

craniocerebral trauma

,

substance-related disorders

,

,

psychological stress

,

,

psychological distress

,

emotional regulation

,

,

,

post-traumatic stress disorders

,

suicidal ideation

,

attempted suicide

,

,

acupuncture therapy

,

drug interactions

,

parkinson disease

,

learning disabilities

,

pain management

,

,

,

,

neurodevelopmental disorders

,

altitude sickness

,

,

pulmonary edema

tissue adhesions

,

healthy volunteers/patients

adolescent behavior

,

musculoskeletal pain

,

psychomotor disorders

,

drinking behavior

,

,

,

,

appetitive behavior

,

psychological codependency

,

insulin resistance

,

kidney diseases

,

renal insufficiency

,

wasting syndrome

,

biological availability

,

child development

,

chronic renal insufficiency

,

drug-related side effects and adverse reactions

,

alcohol withdrawal delirium

,

,

,

retinal degeneration

,

retinitis pigmentosa

,

squamous cell carcinoma of head and neck

,

,

hepatic insufficiency

,

alopecia areata

,

,

chronic kidney failure

,

,

bone marrow diseases

,

,

knee prosthesis

,

therapeutic equivalency

,

,

,

,

,

,

hiv wasting syndrome

,

nociceptive pain

,

,

intervertebral disc degeneration

,

,

chronic periodontitis

,

,

,

,

,

hypercholesterolemia

,

metabolic syndrome

,

,

,

mouth neoplasms

,

patient satisfaction

,

skin absorption

,

musculoskeletal diseases

,

chemical and drug induced liver injury

,

male infertility

,

dentin sensitivity

,

,

driving under the influence

,

addictive behavior

,

,

,

,

pharmacokinetics

,

,

breast neoplasms

,

major depressive disorder

,

,

cigarette smoking

,

alcoholic intoxication

,

ulcerative colitis

,

,

,

sickle cell anemia

,

type 2 diabetes mellitus

,

smoking cessation

,

,

,

,

rheumatoid arthritis

,

obsessive-compulsive disorder

,

,

tobacco smoking

,

colonic neoplasms

,

post-acute covid-19 syndrome

,

,

,

graft vs host disease

,

irritable bowel syndrome

,

,

acquired immunodeficiency syndrome

,

,

substance withdrawal syndrome

,

,

,

neurocognitive disorders

,

,

schizophrenia spectrum and other psychotic disorders

,

psoriatic arthritis

,

memory disorders

,

sleep apnea syndromes

,

compulsive personality disorder

,

reflex sympathetic dystrophy

,

brain neoplasms

,

neurodevelopmental disorders

,

,

colorectal neoplasms

,

multiple myeloma

,

liver neoplasms

,

intellectual disability

,

,

taste disorders

,

heroin dependence

,

sturge-weber syndrome

,

,

,

,

absence epilepsy

,

huntington disease

,

,

,

dystonic disorders

,

,

,

chronic pancreatitis

,

renal circulation

,

,

,

,

complex regional pain syndromes

,

cognition disorders

,

gastrointestinal diseases

,

digestive system diseases

,

nervous system diseases

,

,

,

caregiver burden

,

,

,

,

restless legs syndrome

,

rectal neoplasms

,

gallbladder neoplasms

,

child behavior disorders

,

,

autoimmune hepatitis

,

,

coronavirus infections

,

severe acute respiratory syndrome

,

,

communicable diseases

,

chronic traumatic encephalopathy

,

,

,

hidradenitis suppurativa

,

essential tremor

,

prostatic neoplasms

,

exercise tolerance

,

,

,

,

,

,

aids-associated nephropathy

,

autonomic nervous system diseases

,

primary dysautonomias

,

familial dysautonomia

,

,

olfaction disorders

,

erectile dysfunction

,

pharmacological phenomena

,

amphetamine-related disorders

,

,

allergic rhinitis

,

allergic conjunctivitis

,

,

epidermolysis bullosa simplex

,

epidermolysis bullosa dystrophica

,

junctional epidermolysis bullosa

,

hoarding disorder

,

,

opiate overdose

,

,

,

photorefractive keratectomy

,

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

,

headache disorders

,

,

neuroinflammatory diseases

,

medical sociology

,

carpal tunnel syndrome

,

neuromyelitis optica

,

breast carcinoma in situ

,

,

ductal carcinoma breast

,

intraductal carcinoma noninfiltrating

,

rotator cuff injuries

,

post-traumatic epilepsy

,

hepatocellular carcinoma

,

,

respiratory aspiration

,

,

urinary incontinence

,

combat disorders

,

post-traumatic headache

,

,

,

,

,

,

opioid-related disorders

,

mental disorders

,

marijuana smoking

,

sleep initiation and maintenance disorders

,

peripheral nervous system diseases

,

,

,

autism spectrum disorder

,

,

autistic disorder

,

,

alzheimer disease

,

drug resistant epilepsy

,

somatoform disorders

,

,

,

wounds and injuries

,

parkinson disease

,

,

,

sleep wake disorders

,

inflammatory bowel diseases

,

tourette syndrome

,

diabetes mellitus

,

,

problem behavior

,

diabetic neuropathies

,

traumatic brain injuries

,

psychomotor agitation

,

spinal cord injuries

,

,

generalized anxiety disorder

,

,

obstructive sleep apnea

,

,

,

,

infantile spasms

,

,

palliative care

,

systemic scleroderma

,

temporomandibular joint disorders

,

,

migraine disorders

,

,

,

,

prader-willi syndrome

,

chronic obstructive pulmonary disease

,

postoperative nausea and vomiting

,

anorexia nervosa

,

,

sexual behavior

,

diffuse scleroderma

,

neoplasm metastasis

,

temporomandibular joint dysfunction syndrome

,

feeding and eating disorders

,

heart disease risk factors

,

cardiovascular diseases

,

bipolar and related disorders

,

polyneuropathies

,

trichotillomania

,

,

,

,

sexually transmitted diseases

,

postherpetic neuralgia

,

,

electromyography

,

,

,

,

,

,

,

,

overactive urinary bladder

,

vascular dementia

,

alcohol abstinence

,

stress fractures

,

excoriation disorder

,

,

tobacco use cessation

,

behavioral symptoms

,

,

pervasive child development disorders

,

,

peripheral nerve injuries

,

occlusal splints

,

psychological burnout

,

severe acute respiratory syndrome-related coronavirus

,

,

urinary calculi

,

,

protein-energy malnutrition

,

,

,

attention deficit and disruptive behavior disorders

,

dermatomyositis

,

,

spinal cord diseases

,

secondary headache disorders

,

male breast neoplasms

,

,

anterior cruciate ligament injuries

,

,

tibial meniscus injuries

,

tension-type headache

,

mucopolysaccharidosis iii

,

mixed dementias

,

,

,

,

marijuana abuse

,

,

substance-related disorders

,

,

healthy volunteers/patients

,

,

psychotic disorders

,

multiple sclerosis

,

,

,

alcohol drinking

,

post-traumatic stress disorders

,

anxiety disorders

,

,

,

muscle spasticity

,

,

tobacco use disorder

,

myoclonic epilepsies

,

knee osteoarthritis

,

postoperative pain

,

,

,

cognitive dysfunction

,

bipolar disorder

,

depressive disorder

,

lennox gastaut syndrome

,

traumatic stress disorders

,

,

,

attention deficit disorder with hyperactivity

,

myofascial pain syndromes

,

,

tuberous sclerosis

,

,

alcohol-related disorders

,

amyotrophic lateral sclerosis

,

pancreatic neoplasms

,

dual (psychiatry) diagnosis

,

motor neuron disease

,

,

replacement arthroplasty knee

,

cocaine-related disorders

,

hyperemesis gravidarum

,

,

follicular lymphoma

,

psychological well-being

,

,

drug interactions

,

magnetic resonance imaging

,

head and neck neoplasms

,

cannabinoid hyperemesis syndrome

,

,

,

,

,

,

esophageal diseases

,

induced abortion

,

liver cirrhosis

,

accidental injuries

,

respiratory insufficiency

,

,

adolescent development

,

underage drinking

,

recreational drug use

,

,

risk reduction behavior

,

personality disorders

,

electroencephalography

,

x-linked genetic diseases

,

intractable pain

,

,

,

intestinal diseases

,

health risk behaviors

,

impulsive behavior

,

transcranial magnetic stimulation

,

,

hiv seropositivity

,

health behavior

,

,

,

suicidal ideation

,

localized scleroderma

,

,

,

,

,

central nervous system diseases

,

,

psychological inhibition

,

positron-emission tomography

,

hypersensitivity

,

,

phenylketonurias

,

,

psychological feedback

,

appetite regulation

,

,

eosinophilic esophagitis

,

,

,

thromboangiitis obliterans

,

,

brain concussion

,

ankylosing spondylitis

,

spondylarthritis

,

,

,

genetic predisposition to disease

,

,

cerebellar diseases

,

ischemic stroke

,

central nervous system neoplasms

,

spinal cord neoplasms

,

nervous system neoplasms

,

,

spinal neoplasms

,

teratozoospermia

,

oxidative stress

,

intraocular pressure

,

shared paranoid disorder

,

crisis intervention

,

,

obstructive lung diseases

,

criminal behavior

,

abdominal obesity

,

,

,

postoperative complications

,

cystic fibrosis

,

atherosclerosis

,

alcohol drinking in college

,

,

patient acceptance of health care

,

,

,

fetal growth retardation

,

placenta diseases

,

language disorders

,

hematologic neoplasms

,

,

maternal behavior

,

human influenza

,

,

psychotic affective disorders

,

prediabetic state

,

glucose intolerance

,

,

,

occupational stress

,

attitudes health knowledge practice

,

pregnancy complications

,

ambulatory care

,

surveys and questionnaires

,

premature birth

,

atrial premature complexes

,

ventricular premature complexes

,

signs and symptoms

,

,

neonatal abstinence syndrome

,

gastric emptying

,

,

,

neurobehavioral manifestations

,

,

,

,

eye manifestations

,

immune system diseases

,

,

family characteristics

,

non-small-cell lung carcinoma

,

non-hodgkin lymphoma

,

,

,

photosensitivity disorders

,

circadian rhythm

,

hip osteoarthritis

,

expressed emotion

,

bariatric surgery

,

treatment-resistant depressive disorder

,

,

pain management

,

retrospective studies

,

color vision defects

,

wiskott-aldrich syndrome

,

,

rem sleep behavior disorder

,

sleep arousal disorders

,

,

bulimia nervosa

,

binge-eating disorder

,

respiration disorders

,

behavioral economics

,

emotional regulation

,

perinatal mortality

,

Antineoplaston a10

diabetes mellitus

,

healthy volunteers/patients

,

,

chronic kidney failure

,

bullous pemphigoid

,

hemolytic anemia autoimmune

,

clostridium infections

,

breast neoplasms

,

erectile dysfunction

,

lower urinary tract symptoms

,

atopic dermatitis

,

,

pharmacokinetics

,

chronic obstructive pulmonary disease

,

respiratory aspiration

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

,

small cell lung carcinoma

,

medical sociology

,

renal insufficiency

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

neuroinflammatory diseases

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hematologic neoplasms

,

,

biological availability

,

,

non-small-cell lung carcinoma

,

postcoital contraception

,

ovulation inhibition

,

breast neoplasms

,

,

atrial fibrillation

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

cardiomyopathies

,

cardiovascular diseases

,

parkinson disease

,

,

,

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

ovarian neoplasms

,

peripheral nervous system diseases

,

ovarian epithelial carcinoma

,

,

skin abnormalities

,

myocardial infarction

,

,

acquired immunodeficiency syndrome

,

peripheral arterial disease

,

magnetic resonance angiography

,

,

pulmonary hypertension

,

left ventricular dysfunction

,

ventricular dysfunction

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

venous thromboembolism

,

thromboembolism

,

chronic renal insufficiency

,

surgical blood loss

,

non-hodgkin lymphoma

,

,

,

venous thrombosis

,

multiple sclerosis

,

hyperphosphatemia

,

,

prostatic neoplasms

,

postoperative hemorrhage

,

,

pulmonary embolism

,

,

,

essential hypertension

,

,

kidney diseases

,

peripheral vascular diseases

,

bacterial infections

,

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

magnetic resonance imaging

,

brain neoplasms

,

,

memory disorders

,

,

,

depressive disorder

,

spinal cord injuries

,

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

healthy volunteers/patients

,

,

,

,

,

communicable diseases

,

,

diabetes mellitus

,

,

type 2 diabetes mellitus

,

relapsing-remitting multiple sclerosis

,

,

atopic dermatitis

,

renal cell carcinoma

,

,

acute coronary syndrome

,

coronary artery disease

,

tension-type headache

,

,

chronic bronchitis

,

,

,

,

,

,

physiological sexual dysfunction

,

colorectal neoplasms

,

urinary tract infections

,

,

,

respiratory tract infections

,

,

macular degeneration

,

energy metabolism

,

community-acquired pneumonia

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

gene expression

,

cell proliferation

,

,

neoplasm metastasis

,

central nervous system neoplasms

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